High-yield continuous lentiviral vector bioprocessing through perfusion intensification and integrated cold chain affinity capture
Perfusion intensification, cold harvest stabilization, and inline affinity capture together can more than double lentiviral vector (LVV) recovery while removing steps from the process. This session presents a continuous LVV workflow that reached around 12 × 10⁶ viable cells/mL before transfection and delivered roughly 16-fold higher cumulative transduction units over 3 days through cold harvest handling. Keen Chung, Technical Lead…