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DTSTART;TZID=Europe/London:20260909T160000
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UID:731-1788969600-1788973200@advancedtherapieswales.co.uk
SUMMARY:Delivering confidence in precision medicine: strategies for potency\, safety\, and long-term success
DESCRIPTION:This webinar explores the scientific and analytical capabilities required to support precision medicine programs across advanced modalities such as cell and gene therapy\, and complex therapeutic areas\, including oncology and neurology. \nJoin an expert panel as they explore key considerations in potency assessment\, safety monitoring and evidence generation\, with a focus on building integrated strategies that support development from early research through long-term follow-up. \nRegister now to explore real-world perspectives on:  \n\nDefining and measuring clinically meaningful potency across CAR-T\, in vivo gene therapy\, and other CGT modalities\, and how potency strategy evolves from early development through regulatory submission\nDesigning safety monitoring programs that extend beyond clinical trials\, including long-term follow-up\, registries\, and modality-specific risks such as immunogenicity and insertional mutagenesis\nIntegrating analytical data\, clinical endpoints\, and real-world evidence into a cohesive evidence strategy that supports regulatory and payer expectations\n\nHow manufacturing consistency\, analytical controls\, and cross-functional alignment contribute to sustained program confidence post-approval. \n  \nFind our more here
URL:https://advancedtherapieswales.co.uk/event/delivering-confidence-in-precision-medicine-strategies-for-potency-safety-and-long-term-success/
LOCATION:Online
CATEGORIES:Webinar
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DTSTART;TZID=Europe/London:20260916T160000
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UID:734-1789574400-1789578000@advancedtherapieswales.co.uk
SUMMARY:Transitioning to serum-free T cell manufacturing: process considerations and cross-platform scale-up data
DESCRIPTION:Serum is one of the largest sources of variability in T cell manufacturing\, driving lot-to-lot inconsistency\, sourcing constraints\, and contamination risk. This data-led session shows you how a chemically defined\, serum-free workflow removes that dependency\, so you can build more reproducible processes from early development through clinical scale. \nChengkang Zhang will walk through experimental data on the impact of serum removal at each stage of manufacturing: improved lentiviral vector transduction efficiency\, robust T cell expansion in serum-free culture\, and clinical-scale performance across multiple platforms. You will see cross-platform results spanning T-flasks\, G-Rex\, Xuri\, and Cocoon systems\, plus practical evidence on how oxygen transfer and media exchange strategies shape expansion outcomes. \nAttend this webinar to: \n\nTake away a data-backed framework for evaluating and implementing serum-free T cell culture in your own workflows\nSee experimental data showing improved lentiviral vector transduction efficiency and consistent expansion after serum removal\nCompare cross-platform scale-up performance across T-flasks\, G-Rex\, Xuri\, and Cocoon systems\, from research through clinical manufacturing\nLearn the critical success factors that determine a successful transition\, including cell handling\, media management\, and dissolved oxygen control\n\nChengkang (CK) Zhang\, Associate Director\, R&D\, Lonza\, brings extensive experience in mammalian cell culture and chemically defined media development for cell therapy\, and is the inventor of several cell culture technology patents. \nFind out more
URL:https://advancedtherapieswales.co.uk/event/transitioning-to-serum-free-t-cell-manufacturing-process-considerations-and-cross-platform-scale-up-data/
LOCATION:Online
CATEGORIES:Webinar
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